We exist to improve the lives
of everyone affected by epilepsy

Lamotrigine "appears safe" for use during pregnancy

8 January, 2004

A small-scale
study has found that the anti-epileptic drug lamotrigine may be
"relatively safe" for women with epilepsy
to take during pregnancy.

Writing in the
journal Acta
Neurologica Scandinavica
, researchers, led by Dr Anne
Sabers from the Danish
Epilepsy Hospital
in Glostrup,
studied 147 pregnancies in women taking lamotrigine, oxcarbazepine
and valproate. Of the entire group taking anti-epileptic medication,
the risk of birth malformations was 3.1 per cent, however of the
group
taking
lamotrigine
the risk
was only 2.0 per cent. In comparison the risk of birth malformations
in women taking valproate was 6.7 per cent.

Dr Sabers noted that the small number of participants in the study
meant that no conclusions could be drawn from this study but hoped
that future large scale studies would be able to provide more information
about the risks involving with each anti-epileptic drug.