Computer model uses EEG data to predict epilepsy medicine effectiveness

28 Oct 2021

A new study from Italy has shown that a computer model using electroencephalogram (EEG) data can predict whether a person will respond to the epilepsy medicine levetiracetam.

The researchers, Pierpaolo Croce and colleagues, created a machine learning model based on data from EEG tests, which are used to record brain activity in people with epilepsy. Machine learning models are computer programs that process data and can use that to create predictions for new data.

The group used EEG data from 23 people with temporal lobe epilepsy to test whether it can predict how well levetiracetam would work.

EEGs were done before people started to take levetiracetam and three months after starting. After two years of the study participants taking the medicine, the researchers grouped them into those who were seizure free and those who were not seizure free.

The team found 152 features in the EEG data that could help predict whether a person’s medicine would work for them or not. Their machine model showed that it could predict the effectiveness of levetiracetam in about three quarters of cases when using just data from before the medicine was started. When using data from before the medicine was taken and data from three months after starting, the model could predict correctly in about four in five cases.

The study, published in the journal Clinical Neurophysiology, concluded that this shows the possibilities of machine learning models using EEG data in predicting medicine effectiveness in people with epilepsy. The researchers added that future studies should use this to try to develop a model that can match people with epilepsy to the epilepsy medicine most likely to work for them. 

 

You may also be interested in...

New MEG imaging technology improves accessibility to children

New technology to make magnetoencephalography (MEG) brain imaging more accessible in children has been developed by UK scientists and Young Epilepsy.

There are no comments yet. Be the first to comment...

Question about your epilepsy?

Your question will be sent to our helpline advisors.

Have a comment about this page?

All comments are reviewed by a moderator before publishing. Comments will be edited or deleted if they are offensive, libellous, slanderous, abusive, commercial or irrelevant.

We ask for your email when you make a comment through this website. This means that we can let you know directly that we have replied to you. By making a comment through the website, you allow us to use the comment in our publicity without using your name. If we would like to use your name, we will email you to get your permission.

The content of this field is kept private and will not be shown publicly.
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
7 + 13 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.