We exist to improve the lives
of everyone affected by epilepsy

Landau Kleffner Syndrome


What is a syndrome?

A syndrome is a group of signs and symptoms that, added together, suggest a particular medical condition. In epilepsy, examples of these signs and symptoms would be things like the age at which seizures begin, the type of seizures, whether the child is male or female and whether they have physical or learning disabilities, or both. The results of an electroencephalogram (EEG) are also used to help identify epilepsy syndromes.

Epilepsy Action has more information about seizure types, learning disabilities, and the EEG

If you would like to know more about an epilepsy syndrome, please speak to your doctor. If you would like to know more about epilepsy in general, please contact Epilepsy Action.

Landau-Kleffner syndrome

Landau-Kleffner syndrome (LKS) is an age-related epilepsy syndrome of childhood. Its main features are a loss of speech and language skills, with seizures. The speech and language skills may improve over time. LKS usually starts before the age of six years and affects twice as many boys as girls. The underlying cause of LKS is not yet known.


The first symptoms are either epileptic seizures or problems with understanding and speaking words. The difficulty with language becomes obvious with the child not being able to recognise voices, or the content of conversations. This is called ‘verbal auditory agnosia’. Children with LKS are often mistakenly thought to have hearing loss.

Later on, children may have difficulty telling the difference between other, non-language based sounds such as the doorbell ringing or a dog barking. The language difficulties may then worsen and speech may become affected. Children may have difficulties expressing themselves, may talk nonsense or in jargon, or even stop speaking altogether.

Behaviour problems such as hyperactivity and attention deficits are also common. Attention deficit hyperactivity disorder (ADHD), and attention deficit disorder (ADD) refer to a range of problem behaviours associated with poor attention span. These behaviours may include impulsiveness, restlessness and hyperactivity, as well as inattentiveness. They often prevent children from learning and socialising well.

The severity of the language and behavioural problems varies over time.

Epileptic seizures develop in about three quarters of children with LKS. The seizures are usually infrequent and respond well to treatment. A variety of seizure types can develop, including tonic-clonic seizures, focal seizures, prolonged absences and drop attacks. Seizures happen most commonly during the night.


A standard EEG may show abnormalities over a specific area of the brain called the temporal lobe. The doctor may want to organise a more prolonged EEG recording, particularly one during sleep. This is because the abnormalities seen on a routine recording become more pronounced and persistent during sleep. The EEG can sometimes also be used to monitor progress and response to treatment. Magnetic resonance imaging (MRI) and computed tomography (CT) brain scans are usually normal. A neuropsychology assessment (study of the central nervous system) is also useful to look at the particular pattern of difficulties a child may have. This is important in planning educational needs, for monitoring progress and response to treatment.

Epilepsy Action has more information about diagnosing epilepsy


Although the seizures of LKS usually respond well to treatment with epilepsy medicines, the speech and language difficulties can be much more of a problem. Response to treatment can be assessed in different ways, including an improvement in the child's language abilities, an improvement in the EEG abnormalities, and seizure control.

Commonly used medicines include sodium valproate (Epilim), ethosuximide (Zarontin) and clobazam (Frisium). A steroid called prednisolone and a medicine called sulthiame (Ospolot) may also be helpful. Sometimes two epilepsy medicines are given together, such as sodium valproate and prednisolone. A combination of two or three medicines may also be used. If these medicines fail, steroid medicines may be used, usually for short periods. There are two or three different preparations of steroids.

If treatment with epilepsy medicines fails, there is an option to look into a highly specialised form of brain surgery called subpial transection. This procedure is only carried out in a few specialist centres, and may not be suitable for every child with LKS.

Children should also be seen and treated by a speech and language therapist and an educational psychologist to help with their speech and educational problems.

Information about treatments for children can be found on the Medicines for Children website.

There may be research studies open that are relevant to this epilepsy syndrome. Your child’s doctor will be able to discuss this with you.

If your child has this syndrome they may have prolonged or repeated seizures. Your child’s doctor will discuss a ‘rescue’ or emergency care plan with you to treat any prolonged or repeated seizures.


Although the outlook for seizures in children with LKS is good, many children will be left with significant language, learning and behavioural difficulties. The seizures usually stop by the age of 15, although a small number (about one in 10) continue to have infrequent seizures. Only 10-20 out of a hundred children with Landau-Kleffner syndrome will have normal language and learning abilities in adulthood.


Contact a Family
 Freephone helpline (UK only): 0808 808 3555
 Website: cafamily.org.uk
 Email: info@cafamily.org.uk 


Our thanks

Epilepsy Action would like to thank
•Dr Richard Appleton, and Dr Rachel Kneen, consultant paediatric neurologists at Alder Hey Children’s Hospital, Liverpool, UK and
• Dr Stewart Macleod, consultant paediatric neurologist at Royal Hospital for Sick Children, Glasgow, UK.
 They have kindly prepared the information on this page. It is based on their own research, experience and expertise.

This information is exempt under the terms of The Information Standard.

  • Updated May 2014
    To be reviewed May 2017

Comments: read the 4 comments or add yours


Hello I am Shannon I am 18 years old It is unclear when I got LKS. My seizures started when I was 7 years old I got them during night time and would be very confused the next day when I would wake up, but doctors didn't know what kind of epilepsy I had as my EEG's where all over the place they put me on Ospolote, which got helped. I always had problems with language and hearing difficulties but doctors never knew why. When I was born doctors thought I was brain damaged or autistic but I proved them wrong!!! with 8 years i went to boarding school for the death in Germany which helped. When i was 12 years old everything got worse i started to stutter wasn't able to write i started to put weird letters into words most common ones were g,h,j,k,nor talk probably my hearing got worse which then my papernts and i decided to put me into a school for people with learning difficulties which helped because i needed the time off and take it slow. It was so frustrating i hated it i was scared to go into a job and ask people for help i always asked my sister to get something for me. I was just so angry that i always had to work that extra hard. I attended speech and language therapy to help me and find strategies. After two year it just mate click i started to write again my speech got better. My parents and i decided to put me into a mainstream school which was very hard as my understanding of language wasn't the best. After 1 and a half year i got moved to a british army school to learn English as we where moving to Scotland due to my dad being in the army. Which was quite the adjustment as i always felt safe in schools were people had some kind of diability and now being in school were no one understood what was going on. Now i live in Scotland i just finished school. And going to college soon. My mum was the one reading about LKS when i was sick and she always he;lped me with my homework and never gave up and always encouraged me to write even tho no one understood a word. Im still wearing hearing aids i don't have any seizures anymore but i'm left over with these language progressing problem which is frustrating.
I would love to meet people who have LKS and talk to them. Thank you shannon

Submitted by Shannon on

Hi Shannon
That’s quite some story! And so many challenges that you’ve come through.

I am linking you to the contact details for people who are on the Contact a Family site. These are the ones listed as having or caring for someone with LKS. You could also see if you can contact someone on our online community, forum4e.

I really hope you are able to link up with some people in a similar situation.

Epilepsy Action Advice and Information Team

Submitted by Cherry, Epileps... on

Do people think I've got the wrong epilepsy? I'm deaf in both ears, epileptic since about 6 years old, autistic and learning difficulties but didn't find out till I was about 12 years old. I'm 24 years old now.

Submitted by Sophie Grundy on

Hi Sophie
That’s a difficult one. It isn’t possible to have a test for Landau-Kleffner syndrome.

My best suggestion is that you ask your GP to look back through your notes in case there is anything useful from your original diagnosis. If (and it is a fairly big if) there are any EEG results there, a specialist may be able to look at them to check your diagnosis.

I hope that’s helpful.
Epilepsy Action Advice and Information Team

Submitted by Cherry, Epileps... on